| 摘要 |
The present invention is to provide a novel compound (I), having the anti-virus activity, particularly the HIV integrase inhibitory activity, and a drug containing the same, particularly an anti-HIV drug, as well as a process and an intermediate thereof. Compound (I) wherein Zis NR; Ris hydrogen or lower alkyl; X is a single bond, a hetero atom group selected from O, S, SO, SOand NH, or lower alkylene or lower alkenylene in which the hetero atom group may intervene; Ris optionally substituted aryl; Ris hydrogen, a halogen, hydroxy, optionally substituted lower alkyl etc; and Rand Zpart taken together forms a ring, to form a polycyclic compound, including e.g., a tricyclic or tetracyclic compound., (I) |
