| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a genetic deletion mutant live E. coli vaccine suitable for mass application to poultry, including chickens. <P>SOLUTION: There is provided the Escherichia coli aroA-microorganism having the identifying characteristics of the strain and provides a vaccine composition which comprises an immunogenically effective amount of the E. coli mutant with identifying characteristics of E. coli aroA-PTA-5094 and a pharmacologically acceptable carrier. Also provided is a safe and effective method to protect poultry against the ravages of Escherichia coli bacillosis infection and disease in which a live mutant aroA-gene deleted E. coli immunogen is administered to chickens, turkeys and the like via mass application routes such as coarse sprays and drinking water. <P>COPYRIGHT: (C)2012,JPO&INPIT |
