| 发明名称 |
METHOD OF TREATMENT |
| 摘要 |
The invention provides methods for inducing apoptosis, comprising treatment of a patient with a TNFα inhibitor as well as with an IAP inhibitor and a TRAIL receptor agonist. The methods ameliorate the risk of unwanted effects, thereby resulting in an improved therapeutic index for IAP inhibitors in combination with a TRAIL receptor agonist. |
| 申请公布号 |
US2011287001(A1) |
申请公布日期 |
2011.11.24 |
| 申请号 |
US200913063307 |
申请日期 |
2009.08.05 |
| 申请人 |
TETRALOGIC PHARMACEUTICALS;AMGEN INC. |
发明人 |
HOLLAND PAMELA M.;PIASECKI JULIA C.;BENETATOS CHRISTOPHER A.;CHUNDURU SRINIVAS K.;MCKINLAY MARK A. |
| 分类号 |
A61K39/395;A61K38/17;A61P35/04 |
主分类号 |
A61K39/395 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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