| 发明名称 |
MODIFIED PROTEIN WHICH BINDS TO EXTRACELLULAR MATRIX COMPONENT |
| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a targeted delivery of the therapeutic genes to impaired, diseased, or transplanted blood vessel. <P>SOLUTION: A proteoliposome includes a wall, wherein the wall of the proteoliposome includes a targeting polypeptide including a binding region which binds to an extracellular matrix component. A vector particle has a modified viral surface protein for targeting the vector particle to an extracellular matrix component, wherein the viral surface protein is modified to include a targeting polypeptide including a binding region which binds to an extracellular matrix component. <P>COPYRIGHT: (C)2012,JPO&INPIT |
| 申请公布号 |
JP2011234740(A) |
申请公布日期 |
2011.11.24 |
| 申请号 |
JP20110176306 |
申请日期 |
2011.08.11 |
| 申请人 |
UNIV OF SOUTHERN CALIFORNIA |
发明人 |
HALL FREDERICK L;GORDON ERLINDA MARIA;ANDERSON W FRENCH;STARNES VAUGHN A |
| 分类号 |
C12N15/09;A61K9/127;A61K31/7088;A61K35/76;A61K38/00;A61K48/00;A61P1/16;A61P7/02;A61P9/00;A61P9/10;A61P17/02;A61P19/02;A61P19/04;A61P27/02;A61P29/00;A61P35/00;A61P43/00;C07K5/00;C07K14/08;C07K14/15;C07K14/16;C07K14/755;C07K14/78;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N7/00;C12N7/01;C12N15/86;C12N15/867 |
主分类号 |
C12N15/09 |
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