摘要 |
Disclosed is a vaccine comprising Newcastle disease virus-like particles, said particles comprising a Newcastle disease viral matrix protein. The disclosed vaccine is used in the manufacture of a medicament for immunizing a host susceptible to Newcastle disease with said vaccine under conditions such that antibodies directed to said virus-like particle are produced. Also encompassed by the specification is a method, comprising; a) providing, i. an expression vector comprising DNA sequences encoding a Newcastle disease matrix protein; ii. a cell capable of being transfected by said vector; b) transfecting said cell with said vector under conditions such that Newcastle disease virus-like particles are generated, provided said cell is not within a human. |