发明名称 |
NOVEL PYRROLO[2,3-D]PYRIMIDINE COMPOUND |
摘要 |
<p>Provided is a novel pyrrolo[2,3-d]pyrimidine compound which has GPR119 receptor agonistic activity and is useful as a drug. Specifically provided is a compound represented by formula [I] or a pharmacologically acceptable salt thereof. In formula [I], E is -NH- or the like; A is a substituted benzene ring represented by formula (A-i), or the like; R01A and R01B may be the same or different and are each hydrogen, halogen, or the like; R02 is alkylthio or the like; R03 is hydrogen or alkyl; R04 is alkyl or the like; R05 is alkylsulfonyl; Q is a single bond or alkylene; R0 is a cyclic group represented by formula (R-iii), or the like; R1 is acyl represented by formula: R11OCO- [wherein R11 is alkyl which may be substituted by one to three halogen atoms], or the like; R2 is halogen; and R3 is hydrogen or the like.</p> |
申请公布号 |
WO2011145718(A1) |
申请公布日期 |
2011.11.24 |
申请号 |
WO2011JP61625 |
申请日期 |
2011.05.20 |
申请人 |
MITSUBISHI TANABE PHARMA CORPORATION;TSUBOI, YASUNORI;SHIRAI, KIMIHIRO;HONJOU, TAKASHI |
发明人 |
TSUBOI, YASUNORI;SHIRAI, KIMIHIRO;HONJOU, TAKASHI |
分类号 |
C07D487/04;A61K31/519;A61K31/5377;A61K31/541;A61K31/55;A61P3/04;A61P3/06;A61P3/10;A61P9/00;A61P9/10;A61P9/12;A61P43/00;C07D519/00 |
主分类号 |
C07D487/04 |
代理机构 |
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代理人 |
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