| 发明名称 |
HIGH MANNOSE PROTEIN AND METHOD OF MAKING HIGH MANNOSE PROTEIN |
| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a method of making high mannose proteins. <P>SOLUTION: The method of purifying a hmGCB (high mannose glucocerebrosidase) from a sample includes: providing a harvested hmGCB product; and subjecting the hmGCB product to hydrophobic charge induction chromatography (HCIC) or hydrophobic interaction chromatography (HIC); and thereby obtaining a purified hmGCB. <P>COPYRIGHT: (C)2012,JPO&INPIT |
| 申请公布号 |
JP2011236246(A) |
申请公布日期 |
2011.11.24 |
| 申请号 |
JP20110173242 |
申请日期 |
2011.08.08 |
| 申请人 |
SHIRE HUMAN GENETIC THERAPIES INC |
发明人 |
KINOSHITA CAROL A;PRASHSANT MISHRA;BOROWSKI MARIANNE;FRANCIS-DANIEL PETER |
| 分类号 |
C07K1/16;C12N15/09;A61K38/43;A61K38/46;A61K38/47;A61P1/16;A61P1/18;A61P3/06;A61P7/04;A61P7/06;A61P19/08;C12N5/10;C12N9/24;C12N9/99;C12N15/56;C12P21/00 |
主分类号 |
C07K1/16 |
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