| 发明名称 |
BI-SPECIFIC FUSION PROTEINS |
| 摘要 |
Bi-specific fusion proteins with therapeutic uses are provided, as well as pharmaceutical compositions comprising such fusion proteins, and methods for using such fusion proteins to repair damaged tissue. The bi-specific fusion proteins generally comprise: (a) a targeting polypeptide domain that binds to an ischemia-associated molecule; and (b) an activator domain that that detectably modulates the activity of a cellular network.
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| 申请公布号 |
US2011286976(A1) |
申请公布日期 |
2011.11.24 |
| 申请号 |
US201113112907 |
申请日期 |
2011.05.20 |
| 申请人 |
NIELSEN ULRIK;WICKHAM THOMAS;SCHOEBERL BIRGIT;HARMS BRIAN;LINGGI BRYAN;ONSUM MATTHEW;DELABARRE BYRON;MERRIMACK PHARMACEUTICALS |
发明人 |
NIELSEN ULRIK;WICKHAM THOMAS;SCHOEBERL BIRGIT;HARMS BRIAN;LINGGI BRYAN;ONSUM MATTHEW;DELABARRE BYRON |
| 分类号 |
A61K38/16;A61K35/12;A61P9/00;C07H21/04;C07K19/00 |
主分类号 |
A61K38/16 |
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