Method for determining the Cbl-b expression

摘要

The present invention relates to methods for determining intracellular Cbl-b protein in cells of a sample, comprising introducing into a cell an antibody that binds Cbl-b intracellularly, allowing the antibody and potentially present Cbl-b proteins to contact in the cell, detecting binding events between the antibody and Cbl-b, quantifying the detected binding events, whereby the content of Cbl-b protein is determined.