发明名称 |
BONE REPAIR MATERIAL AND METHOD FOR PRODUCING THE SAME |
摘要 |
Bone repair materials are disclosed, from which ions are hardly eluted in living body and which are superior in apatite-forming ability and resistance to apatite peeling and have a scratch resistance high enough for practical use. The material comprises a substrate made of titanium or titanium alloys, and a surface layer, made substantially of titanium oxide, along the surface of the substrate. The substrate has on the surface thereof irregularities of from 1 nm to 10μm in average in both width and depth. The layer has a zeta potential of +4.5 mV or more under an aqueous solution environment of pH 6 to 8, and a critical scratch resistance of 35 mN or more when vibration 100μm in amplitude is added to a stylus with a spring constant of 200 g/mm on the surface layer and the stylus is moved at a rate of 10 mm/sec under a load increasing at a rate of 100 mN/min.
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申请公布号 |
US2011287070(A1) |
申请公布日期 |
2011.11.24 |
申请号 |
US201013147082 |
申请日期 |
2010.01.29 |
申请人 |
KOKUBO TADASHI;MATSUSHITA TOMIHARU;PATTANAYAK DEEPAK K.;CHUBU UNIVERSITY EDUCATIONAL FOUNDATION;ADVANCED MEDIX INC.;SAGAWA PRINTING CO., LTD. |
发明人 |
KOKUBO TADASHI;MATSUSHITA TOMIHARU;PATTANAYAK DEEPAK K. |
分类号 |
A61K33/24;A61K9/00;A61P19/00;C23F1/00 |
主分类号 |
A61K33/24 |
代理机构 |
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