发明名称 BONE REPAIR MATERIAL AND METHOD FOR PRODUCING THE SAME
摘要 Bone repair materials are disclosed, from which ions are hardly eluted in living body and which are superior in apatite-forming ability and resistance to apatite peeling and have a scratch resistance high enough for practical use. The material comprises a substrate made of titanium or titanium alloys, and a surface layer, made substantially of titanium oxide, along the surface of the substrate. The substrate has on the surface thereof irregularities of from 1 nm to 10μm in average in both width and depth. The layer has a zeta potential of +4.5 mV or more under an aqueous solution environment of pH 6 to 8, and a critical scratch resistance of 35 mN or more when vibration 100μm in amplitude is added to a stylus with a spring constant of 200 g/mm on the surface layer and the stylus is moved at a rate of 10 mm/sec under a load increasing at a rate of 100 mN/min.
申请公布号 US2011287070(A1) 申请公布日期 2011.11.24
申请号 US201013147082 申请日期 2010.01.29
申请人 KOKUBO TADASHI;MATSUSHITA TOMIHARU;PATTANAYAK DEEPAK K.;CHUBU UNIVERSITY EDUCATIONAL FOUNDATION;ADVANCED MEDIX INC.;SAGAWA PRINTING CO., LTD. 发明人 KOKUBO TADASHI;MATSUSHITA TOMIHARU;PATTANAYAK DEEPAK K.
分类号 A61K33/24;A61K9/00;A61P19/00;C23F1/00 主分类号 A61K33/24
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