发明名称 |
HCV/GBV-B CHIMERIC VIRUS |
摘要 |
An HCV/GBV-B chimeric virus which maintains the replication function of HCV and is capable of infecting tamarin is disclosed in order to construct an HCV animal model which can be used as a development or evaluation system for therapeutic agents for HCV. The HCV/GBV-B chimeric RNA comprises an RNA of hepatitis C virus and an RNA of GB virus-B, wherein the RNA of hepatitis C virus comprises an RNA encoding leucine at the 1804th position and lysine at the 1966th position in the amino acid sequence of the polyprotein of hepatitis C virus. |
申请公布号 |
US2011289610(A1) |
申请公布日期 |
2011.11.24 |
申请号 |
US200913054356 |
申请日期 |
2009.07.15 |
申请人 |
MAKI NOBORU;MORI KENICHI;FUKAI HIROMI |
发明人 |
MAKI NOBORU;MORI KENICHI;FUKAI HIROMI |
分类号 |
A01K67/027;C07K14/18;C12N5/10;C12N7/01;C12N15/51;C12N15/63 |
主分类号 |
A01K67/027 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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