The invention relates to a marker vaccine for prophylactic treatment of classical swine fever comprising modified live attenuated classical swine fever virus. The viral amino acid sequence of the TAV-epitope of the E2 protein comprises a different sequence from that of a wild-type classical swine fever virus. The invention relates to pharmaceutical compositions of the marker vaccine. The invention also relates to a method of manufacturing marker vaccines for prevention of classical swine fever using selective antibody pressure.
申请公布号
WO2011144360(A1)
申请公布日期
2011.11.24
申请号
WO2011EP02624
申请日期
2011.05.18
申请人
RIEMSER ARZNEIMITTELAG;BEER, MARTIN;BLOME , SANDRA;LEIFER, IMMANUEL