| 发明名称 |
AGENTS AND METHODS FOR DETECTION AND/OR IMAGING OF HYPOXIA |
| 摘要 |
<p>The invention relates to the detection and/or imaging or hypoxia. In particular, the invention relates to the use of 2- nitroimidazoles as agents for the detection and/or imaging of hypoxia. The invention also relates to a method of detecting and/or imaging hypoxic cells using a copper(I)-catalysed azide-alkyne 1,3-dipolar cycloaddition reaction between an alkyne-functionalised nitroimidazole and an azide-functionalised probe or an azide-functionalised nitroimidazole and an alkyne-functionalised probe.</p> |
| 申请公布号 |
WO2011145957(A1) |
申请公布日期 |
2011.11.24 |
| 申请号 |
WO2011NZ00083 |
申请日期 |
2011.05.20 |
| 申请人 |
AUCKLAND UNISERVICES LIMITED;TERCEL, MOANA;PRUIJN, FREDERIK, BASTIAAN |
发明人 |
TERCEL, MOANA;PRUIJN, FREDERIK, BASTIAAN |
| 分类号 |
G01N33/58;C07D233/91;G01N33/53;G01N33/60 |
主分类号 |
G01N33/58 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
