发明名称 PHENYLMORPHOLINES AND ANALOGUES THEREOF
摘要 Provided herein are compounds and prodrugs and methods of preparation of compounds and prodrugs that are capable of functioning as releasers and/or uptake inhibitors of one or more monoamine neurotransmitters, including dopamine, serotonin, and norepinephrine. Also provided are pharmaceutical compositions comprising one or more of these compounds or prodrugs, which may further comprise one or more additional therapeutic agents. Also provided are methods of treatment of various conditions that may be responsive to modification of monoamine neutrotransmitter levels, such as pre-obesity, obesity, addiction, and depression.
申请公布号 CA2800220(A1) 申请公布日期 2011.11.24
申请号 CA20112800220 申请日期 2011.05.20
申请人 RESEARCH TRIANGLE INSTITUTE;UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES,C/O NATIONAL INSTITUTES OF HEALTH, OFFICE OF 发明人 BLOUGH, BRUCE E.;ROTHMAN, RICHARD;LANDAVAZO, ANTONIO;PAGE, KEVIN M.;DECKER, ANN MARIE
分类号 C07D265/30;A61K31/5375;A61P25/16;A61P25/18;A61P25/24 主分类号 C07D265/30
代理机构 代理人
主权项
地址