发明名称 AMINOPYRAZINE DERIVATIVE AND MEDICINE
摘要 The present invention relates to a compound represented by general formula [1] satisfying the following (I) or (II), or a pharmaceutical acceptable salt of the compound. (I) X is CH or N; R1 is a halogen atom,; and R2 is H, a halogen atom, CN, [2], [3], [8], [9], an—O-alkyl, an—O-(saturated ring), etc. [2]:—C(RC)(RD)(RE) (RC to RE each are H, an alkyl, etc.) [3]:—N(RF)(RG) (RF and RG each are H, OH, amino, a (hetero)aryl, etc.) [8]:—C(═O)RL (RL is an alkyl, OH, an alkoxy, amino, etc.) [9]: a (substituted)phenyl; (II) X is >C—C(—O)R3 (R3 is a (substituted)amino, an alkoxy, OH, etc.); R1 is a halogen atom; R2 is H; R3 is H or OH; and R3 and R4 each are H or an alkyl.
申请公布号 US2011288065(A1) 申请公布日期 2011.11.24
申请号 US201013147001 申请日期 2010.02.05
申请人 FUJIHARA HIDETAKA;ASAKI TETSUO;HORI KATSUTOSHI;NAITO HARUNA;NIPPON SHINYAKU CO., LTD. 发明人 FUJIHARA HIDETAKA;ASAKI TETSUO;HORI KATSUTOSHI;NAITO HARUNA
分类号 A61K31/506;A61K31/5377;A61K31/541;A61P35/00;C07D401/14;C07D403/14;C07D413/14;C07D417/14 主分类号 A61K31/506
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