发明名称 |
NOVEL FORMS OF BENDAMUSTINE FREE BASE |
摘要 |
Novel polymorphic forms of bendamustine free base are described, including amorphous bendamustine free base, six anhydrous crystalline forms, four hydrate forms, and five solvate forms, with methods of their preparation and use also being described. |
申请公布号 |
EP2387400(A1) |
申请公布日期 |
2011.11.23 |
申请号 |
EP20100701071 |
申请日期 |
2010.01.14 |
申请人 |
CEPHALON, INC. |
发明人 |
COURVOISIER, LAURENT, D.;EDDLESTON, MARK;HALTIWANGER, CURTIS, R.;MCKEAN, ROBERT, E. |
分类号 |
A61K31/4184;C07D235/16 |
主分类号 |
A61K31/4184 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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