发明名称 |
METHOD FOR THE ASSESSMENT OF SEVERITY OF LIVER CIRRHOSIS |
摘要 |
<p>The present invention is concerned with a method for diagnosing whether a subject suffers from a mild or severe form of liver cirrhosis based on determining the amount of GDF-15 and/or P1GF (Placental Growth Factor) in a sample from said subject and comparing the, thus, determined amount(s) with a reference amount (reference amounts). The method may further comprise determining the amount of adiponectin in a sample from said subject, and comparing said amount to a reference amount for adiponectin. Moreover, the present invention relates to identifying a subject being susceptible to liver transplantation comprising the amount of GDF-15 and/or PlGF (Placental Growth Factor)) in a sample from said subject and comparing the, thus, determined amount(s) with a reference amount (reference amounts). Further encompassed by the present invention are a kit and a device adapted to carry out the method of the present invention.</p> |
申请公布号 |
EP2387720(A1) |
申请公布日期 |
2011.11.23 |
申请号 |
EP20100702028 |
申请日期 |
2010.01.18 |
申请人 |
ROCHE DIAGNOSTICS GMBH;F. HOFFMANN-LA ROCHE AG |
发明人 |
HESS, GEORG;HORSCH, ANDREA;ZDUNEK, DIETMAR |
分类号 |
G01N33/68;G01N33/72;G01N33/74 |
主分类号 |
G01N33/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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