发明名称 |
LONG TERM SUSTAINED RELEASE PHARMACEUTICAL COMPOSITION CONTAINING AQUEOUS SUSPENSION OF BISPHOSPHONATE |
摘要 |
<p>The invention relates to a pharmaceutical composition suitable for injection as an aqueous suspension for sustained release of a bisphosphonate drug, the composition comprising: a sosoloid containing a salt of a bisphosphonate drug; and a salt of a pentavalent phosphorus oxoacid, the sosoloid having a solubility in saline of less than 0.05% by weight as bisphosphonic acid for use as a medicament and for use in the prevention or treatment of a bone disease in a patient, in particular osteoporosis.</p> |
申请公布号 |
EP2120585(A4) |
申请公布日期 |
2011.11.23 |
申请号 |
EP20070862893 |
申请日期 |
2007.12.13 |
申请人 |
AMPHASTAR PHARMACEUTICALS INCORPORATION |
发明人 |
ZHANG, JACK, YONGFENG;LUO, MARY, ZIPING;FEI, DINGYUAN;XIE, KEVIN;DING, JIE, FEI |
分类号 |
A01N57/00;A61K9/20;A61K31/66 |
主分类号 |
A01N57/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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