发明名称 |
METHODS FOR MODULATING SET AND USES THEREOF |
摘要 |
The present invention provides methods for modulating SET activity by contacting SET with a binding agent such as an ApoE peptide derivative. In one embodiment of the invention, a pharmaceutical composition capable of modulating SET activity is administered to a patient for the treatment of an inflammatory or neurological condition. In another embodiment of the invention, compounds efficacious for the treatment of inflammatory and neurological conditions are identified by screening for a binding agent capable of competing with or inhibiting the binding of an ApoE derivative to SET. |
申请公布号 |
EP2052085(A4) |
申请公布日期 |
2011.11.23 |
申请号 |
EP20070870165 |
申请日期 |
2007.12.21 |
申请人 |
COGNOSCI, INC. |
发明人 |
VITEK, MICHAEL P.;CHRISTENSEN, DALE J.;ODDO, JESSICA |
分类号 |
A61K38/17;A61P25/00;A61P37/00 |
主分类号 |
A61K38/17 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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