发明名称 |
METHOD OF TREATING CANCER |
摘要 |
The present invention relates to a method of treating or preventing hyperproliferative disease in a body tissue of a subject, comprising the steps of administering to a subject in need thereof a therapeutically effective amount of an agent that induces double strand breaks in the DNA of the hyperproliferative cells of said body tissue; and subjecting the hyperproliferative cells of said body tissue prior to, simultaneously with or subsequent to step a) to hyperthermia to thereby induce in said cells the degradation, inhibition and/or inactivation of BRCA2. |
申请公布号 |
EP2387403(A1) |
申请公布日期 |
2011.11.23 |
申请号 |
EP20100700073 |
申请日期 |
2010.01.13 |
申请人 |
ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM;ERASMUS UNIVERSITY MEDICAL CENTER ROTTERDAM |
发明人 |
KRAWCZYK, PRZEMYSLAW;ATEN, JACOB A.;KANAAR, ROLAND;ESSERS, JEROEN |
分类号 |
A61K31/517;A61K31/395;A61K45/06;A61P3/00 |
主分类号 |
A61K31/517 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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