发明名称 |
Protein purification by citrate precipitation |
摘要 |
The invention provides methods for isolating proteins in purified form from mixtures by precipitation with citrate. The methods are advantageous in that they effectively separate a protein from lower molecular weight contaminants, including fragments or portions of the protein. Such methods are particularly useful for purifying antibodies from mixtures containing antibody proteolytic fragments and unpaired chains. |
申请公布号 |
US8063189(B2) |
申请公布日期 |
2011.11.22 |
申请号 |
US20100759016 |
申请日期 |
2010.04.13 |
申请人 |
ARUNAKUMARI ALAHARI;FERREIRA GISELA M.;BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
ARUNAKUMARI ALAHARI;FERREIRA GISELA M. |
分类号 |
C07K1/30;C07K1/36 |
主分类号 |
C07K1/30 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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