发明名称 |
Diagnostic histopathology using multiplex gene expression FISH |
摘要 |
The present invention relates to a method for detecting one or more nascent RNAs in a tissue sample using FISH. In the method, a plurality of probes (8 to 82) may be used to detect a single species of nascent RNA. Further, a plurality of nascent RNA species may be detected simultaneously using between 8 and 82 probes for each nascent RNA. The invention comprises, in addition, methods of preparing a sample for nascent RNA detection by reducing autofluorescence of the tissue sample. These techniques may be synergistically combined to achieve significantly improved results.
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申请公布号 |
US8062897(B2) |
申请公布日期 |
2011.11.22 |
申请号 |
US20060404272 |
申请日期 |
2006.04.14 |
申请人 |
CAPODIECI PAOLA;DONOVAN MICHAEL J.;AUREON LABORATORIES, INC. |
发明人 |
CAPODIECI PAOLA;DONOVAN MICHAEL J. |
分类号 |
G01N33/00;C07H21/04;G01N33/53 |
主分类号 |
G01N33/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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