Salts and polymorphs of desazadesferrithiocin polyether analogues as metal chelation agents
摘要
Disclosed herein are new salts and polymorphs of desazadesferrithiocin polyether (DADFT-PE) analogues, as well as pharmaceutical compositions comprising them and their application as metal chelation agents for the treatment of disease. Methods of chelation of iron and other metals in a human or animal subject are also provided for the treatment of metal overload and toxicity.
申请公布号
US8063227(B2)
申请公布日期
2011.11.22
申请号
US20090502559
申请日期
2009.07.14
申请人
TAPPER AMY E.;RIENHOFF, JR. HUGH Y.;PARENT STEPHAN D.;ANDRES PATRICIA;HANKO JASON A.;ZHANG HUAMIN;FERROKIN BIOSCIENCES, INC.
发明人
TAPPER AMY E.;RIENHOFF, JR. HUGH Y.;PARENT STEPHAN D.;ANDRES PATRICIA;HANKO JASON A.;ZHANG HUAMIN