ANTI-ARTHRITIC AGENT USING DICTYOTA CORIACEAE

摘要

PURPOSE: A composition containing Dictyota coriaceae extract or fraction is provided to suppress the expression of MMP-1 and to treat and preventing degenerative arthritis. CONSTITUTION: A pharmaceutical composition for preventing and treating degenerative arthritis or rheumatoid arthritis contains Dictyota coriaceae extract as an active ingredient. A method for preparing the extract comprises: a step of adding 5-50 time(v/w) of water or mixture solvent of water and ethanol to Dictyota coriaceae by enfleurage; a step of filtering and drying the extract; a step of suspending the extract in 1-50 times voluyme(v/w) of water; and a step of fractioning with hexane, chloroform, methylene chloride, or ethyl acetate. A neutraceutical food for preventing and treating degenerative arthritis or rheumatoid arthritis contains the extract as an active ingredient.