| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a plasmon excitation sensor which allows an analyte in a specimen to be more efficiently coupled therewith by providing a porous dielectric layer having a function as a flow path on a surface thereof and allows high-sensitivity measurement by the synergistic effect of this efficient coupling and an improved electric field enhancement effect, and to provide a detection method employing the plasmon excitation sensor. <P>SOLUTION: In the plasmon excitation sensor, a metal thin film is formed on a surface of a transparent dielectric substrate, and the porous dielectric layer having a three-dimensional network skeleton structure and a three-dimensional network pore structure is formed on a surface of the metal thin film, and a ligand is bound to the porous dielectric layer. The detection method according to this invention includes a step of bringing the specimen into contact with the plasmon excitation sensor and a step of detecting generation of an analyte-ligand complex formed in the plasmon excitation sensor by using surface plasmon resonance. <P>COPYRIGHT: (C)2012,JPO&INPIT |
