发明名称 |
Pharmaceutical Compositions with Attenuated Release of Phenolic Opioids |
摘要 |
Pharmaceutical compositions and their methods of use are provided, where the pharmaceutical compositions comprise a phenolic opioid prodrug that provides enzymatically-controlled release of a phenolic opioid, and an enzyme inhibitor that interacts with the enzyme(s) that mediates the enzymatically-controlled release of the phenolic opioid from the prodrug so as to attenuate enzymatic cleavage of the prodrug.
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申请公布号 |
US2011281886(A1) |
申请公布日期 |
2011.11.17 |
申请号 |
US200913121335 |
申请日期 |
2009.10.16 |
申请人 |
JENKINS THOMAS E.;SEROOGY JULIE D.;WRAY JONATHAN W. |
发明人 |
JENKINS THOMAS E.;SEROOGY JULIE D.;WRAY JONATHAN W. |
分类号 |
A61K31/485;A61K31/495;A61K31/496;A61P29/00 |
主分类号 |
A61K31/485 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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