发明名称 |
Linear donor constructs for targeted integration |
摘要 |
Disclosed herein are linear donor molecules comprising homology arms of 50-750 base pairs (e.g., 50-100 base pairs) flanking one or more sequences of interest. The donor molecules and/or compositions comprising these molecules can be used in methods for integration of an exogenous sequence into a specified region of interest in the genome of a cell. |
申请公布号 |
US2011281361(A1) |
申请公布日期 |
2011.11.17 |
申请号 |
US201113134766 |
申请日期 |
2011.06.16 |
申请人 |
DEKELVER RUSSELL;GREGORY PHILIP D.;HOLMES MICHAEL C.;URNOV FYODOR;SANGAMO BIOSCIENCES, INC. |
发明人 |
DEKELVER RUSSELL;GREGORY PHILIP D.;HOLMES MICHAEL C.;URNOV FYODOR |
分类号 |
C12N15/63 |
主分类号 |
C12N15/63 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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