发明名称 |
MEGANUCLEASE VARIANTS CLEAVING A DNA TARGET SEQUENCE FROM THE RHODOPSIN GENE AND USES THEREOF |
摘要 |
The invention relates to meganuclease variants which cleave a DNA target sequence from the human Rhodopsin gene (RHO), to vectors encoding such variants, to a cell, an animal or a plant modified by such vectors and to the use of these meganuclease variants and products derived therefrom for genome therapy, ex vivo (gene cell therapy) and genome engineering including therapeutic applications and cell line engineering. |
申请公布号 |
WO2011141825(A1) |
申请公布日期 |
2011.11.17 |
申请号 |
WO2011IB01495 |
申请日期 |
2011.05.12 |
申请人 |
CELLECTIS;ARNOULD, SYLVAIN;LEMAIRE, FREDERIC |
发明人 |
ARNOULD, SYLVAIN;LEMAIRE, FREDERIC |
分类号 |
C12N15/85;C12N9/22;C12N15/82;C12N15/90 |
主分类号 |
C12N15/85 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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