| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide an apparatus and a method for detecting a change in a membrane potential capable of detecting the change in the membrane potential of a cell in a noninvasive method without labeling the cell membrane. <P>SOLUTION: The apparatus for detecting the change in the membrane potential 1 includes: a light source 106 for reflection interference measurement; a holding section 103 for holding a transparent member 102a mounted with a cell 101; a camera 110 for reflection interference detection for imaging the reflected light which has been emitted from the light source 106 for reflection interference measurement and has been reflected from the cell 101 through the transparent member 102a to form a reflection interference image; and an analysis section 202 for calculating a parameter dI concerning adhesion between the cell 101 and the transparent member 102a from the reflection interference image and detecting the change in the membrane potential of the cell 101 based on the change in the parameter dI. <P>COPYRIGHT: (C)2012,JPO&INPIT |
