<p>The present invention relates to cycloundecadepsipeptide compound analogues presenting mitochondrial permeability transition pore (MPTP) inhibitory activity and reduced cytotoxicity. The present invention further relates to a pharmaceutical composition containing cycloundecadepsipeptide compound and analogues for use in the treatment or prevention of cell death associated disorders or diseases, related to the MPTP opening.</p>
申请公布号
WO2011141891(A1)
申请公布日期
2011.11.17
申请号
WO2011IB52096
申请日期
2011.05.12
申请人
DEBIO RECHERCHE PHARMACEUTIQUE S.A.;VUAGNIAUX, GREGOIRE;GAVILLET, BRUNO;CRABBE, RAFAEL
发明人
VUAGNIAUX, GREGOIRE;GAVILLET, BRUNO;CRABBE, RAFAEL