发明名称 |
SYNTHESIS OF CARBAMOYLPYRIDONE HIV INTEGRASE INHIBITORS AND INTERMEDIATES |
摘要 |
A synthesis approach providing an early ring attachment via a bromination to compound 1-1 yielding compound II-II whereby a final product such as AA can be synthesized. In particular, the 2,4-difluorophenyl-containing sidechain is attached before creation of the additional ring Q. |
申请公布号 |
US2011282055(A1) |
申请公布日期 |
2011.11.17 |
申请号 |
US200913128992 |
申请日期 |
2009.12.08 |
申请人 |
YOSHIDA HIROSHI;TAODA YOSHIYUKI;JOHNS BRIAN;KAWASUJI TAKASHI;NAGAMATSU DAIKI |
发明人 |
YOSHIDA HIROSHI;TAODA YOSHIYUKI;JOHNS BRIAN;KAWASUJI TAKASHI;NAGAMATSU DAIKI |
分类号 |
C07D498/14;C07D471/22 |
主分类号 |
C07D498/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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