发明名称 |
PROCESS FOR SYNTHESIZING OLIGONUCLEOTIDE PHOSPHATE DERIVATIVES |
摘要 |
The present invention describes simple, efficient, and enzyme-free method of making oligonucleotide phosphate derivatives. This invention presents novel process using automated synthesizer for synthesizing oligonucleotide phosphate derivatives using a diaryl phosphonate as reagent. |
申请公布号 |
US2011282044(A1) |
申请公布日期 |
2011.11.17 |
申请号 |
US20100847893 |
申请日期 |
2010.07.30 |
申请人 |
MANOHARAN MUTHIAH;ZLATEV IVAN;ALNYLAM PHARMACEUTICALS |
发明人 |
MANOHARAN MUTHIAH;ZLATEV IVAN |
分类号 |
C07H21/00 |
主分类号 |
C07H21/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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