发明名称 PROCESS FOR SYNTHESIZING OLIGONUCLEOTIDE PHOSPHATE DERIVATIVES
摘要 The present invention describes simple, efficient, and enzyme-free method of making oligonucleotide phosphate derivatives. This invention presents novel process using automated synthesizer for synthesizing oligonucleotide phosphate derivatives using a diaryl phosphonate as reagent.
申请公布号 US2011282044(A1) 申请公布日期 2011.11.17
申请号 US20100847893 申请日期 2010.07.30
申请人 MANOHARAN MUTHIAH;ZLATEV IVAN;ALNYLAM PHARMACEUTICALS 发明人 MANOHARAN MUTHIAH;ZLATEV IVAN
分类号 C07H21/00 主分类号 C07H21/00
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