发明名称 APTAMERS TO TISSUE FACTOR PATHWAY INHIBITOR AND THEIR USE AS BLEEDING DISORDER THERAPEUTICS
摘要 The invention relates generally to the field of nucleic acids and more particularly to aptamers that bind to TFPI, which are useful as therapeutics in and diagnostics of bleeding disorders and/or other diseases or disorders in which TFPI has been implicated. In addition, the TFPI aptamers may be used before, during and/or after medical procedures to reduce complications or side effects thereof. The invention further relates to materials and methods for the administration of aptamers that bind to TFPI.
申请公布号 US2011281938(A1) 申请公布日期 2011.11.17
申请号 US201113026165 申请日期 2011.02.11
申请人 SCHAUB ROBERT;MCGINNESS KATHLEEN;NELSON JENNIFER;GENGA RYAN;WATERS EMILY;KURZ JEFFREY;DIENER JOHN;BAXTER HEALTHCARE S.A.;BAXTER INTERNATIONAL INC. 发明人 SCHAUB ROBERT;MCGINNESS KATHLEEN;NELSON JENNIFER;GENGA RYAN;WATERS EMILY;KURZ JEFFREY;DIENER JOHN
分类号 A61K31/7088;A61P1/16;A61P7/00;A61P7/04;C07H21/00;C07H21/02 主分类号 A61K31/7088
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