HPOX COMPOUND, MANUFACTURING METHOD THEREOF, PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATMENT OF INFLAMMATORY DISEASE, DRUG DELIVERY VECTOR AND IMAGING CONTRAST AGENTS COMPRISING HPOX COMPOUND AS AN EFFECTIVE COMPONENT

摘要

PURPOSE: An HPOX(HBA-incorporatred copolyoxalate) compound is provided to ensure anti-inflammation and antioxidant effects by effectively reducing the concentration of NO and internal hydrogen peroxides through a target specific method. CONSTITUTION: An HPOX(HBA-incorporatred copolyoxalate) compound includes oxalyl chloride in which at least one monomer of 4-hydroxybenzly alcohol and vanillyl alcohol is integrated to a polymer skeleton. Nanoparticles are produced by performing polycondensation of oxalate, 1,4-cyclohexanedimethanol, and one or more monomers selected from the group consisting of 4-hydroxybenzyl alcohol and vanillyl alcohol.