发明名称 Process for preparing (S)-(+)-N-methyl-3-(1-naphthyloxy)-3-(2-thienyl)propylamine by using an optically active methylhydroxylaminopropanol compound as intermediate
摘要 The present invention provides (S)-methylhydroxylaminopropanol compound as an intermediate in preparation of (S)-(+)-N-methyl-3-(1-naphthyloxy)-3-(2-thienyl)propylamine. The present invention also provides a process for preparing (S)-(+)-N-methyl-3-(1-naphthyloxy)-3-(2-thienyl)propylamine with higher yield and lower cost by using the (S)-methylhydroxylaminopropanol compound as an intermediate.
申请公布号 EP2386549(A1) 申请公布日期 2011.11.16
申请号 EP20100162440 申请日期 2010.05.10
申请人 SCI PHARMATECH, INC. 发明人 CHEN, BO-FENG;LU, FENG-JU;YEH, JINUN-BAN;WONG,, WEICHYUN
分类号 C07D333/16 主分类号 C07D333/16
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