发明名称 |
4-(2,6-DICHLORO-BENZOYLAMINO)-1H-PYRAZOLE-3-CARBOXYLIC ACID PIPERIDIN-4-YLAMIDE ACID ADDITION SALTS AS KINASE INHIBITORS |
摘要 |
The invention provides an acid addition salt of 4-(2,6-dichloro-benzoylamino)-1H-pyrazole-3-carboxylic acid piperidin-4-ylamide and crystals thereof, the salt being formed with an acid selected from methanesulphonic acid and acetic acid and mixtures thereof. Also provided are the novel uses of salts of 4-(2,6-dichloro-benzoylamino)-1H-pyrazole-3-carboxylic acid piperidin-4-ylamide, processes for the preparation of 4-(2,6-dichloro-benzoylamino)-1H-pyrazole-3-carboxylic acid piperidin-4-ylamide and its salts and novel chemical intermediates.
|
申请公布号 |
US2011274616(A1) |
申请公布日期 |
2011.11.10 |
申请号 |
US201113188887 |
申请日期 |
2011.07.22 |
申请人 |
ASTEX THERAPEUTICS LIMITED |
发明人 |
WYATT PAUL GRAHAM;REES DAVID CHARLES;VINKOVIC MLADEN;TREWARTHA GARY |
分类号 |
A61K51/00;A61K31/454;A61K39/395;A61P1/00;A61P1/16;A61P3/10;A61P7/06;A61P9/00;A61P13/12;A61P17/06;A61P19/02;A61P19/10;A61P25/00;A61P25/16;A61P25/28;A61P31/00;A61P31/12;A61P31/18;A61P35/00;A61P35/02;A61P37/00;C07D401/12 |
主分类号 |
A61K51/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|