发明名称 TETRAZOLONES AS INHIBITORS OF FATTY ACID SYNTHASE
摘要 Provided herein are tetrazolone FASN inhibitors of the formula (I): (I) or a pharmaceutically acceptable form thereof; wherein the variables RA, RB and RC are defined herein. Also provided herein are pharmaceutical compositions of the compounds provided herein as well as methods of their use for the treatment of various disorders such as hyperproliferative disorders, inflammatory disorders, obesity-related disorders and microbial infections.
申请公布号 WO2011140190(A1) 申请公布日期 2011.11.10
申请号 WO2011US35141 申请日期 2011.05.04
申请人 INFINITY PHARMACEUTICALS;BAHADOOR, ADILAH;CASTRO, ALFREDO, C.;CHAN, LAWRENCE, K.;KEANEY, GREGG, F.;NEVALAINEN, MARTA;NEVALAINEN, VESA;PELUSO, STEPHANE;SNYDER, DANIEL, A.;TIBBITTS, THOMAS, T. 发明人 BAHADOOR, ADILAH;CASTRO, ALFREDO, C.;CHAN, LAWRENCE, K.;KEANEY, GREGG, F.;NEVALAINEN, MARTA;NEVALAINEN, VESA;PELUSO, STEPHANE;SNYDER, DANIEL, A.;TIBBITTS, THOMAS, T.
分类号 C07D257/04;A61K31/41;A61P3/00;A61P29/00;A61P35/00;C07D401/06;C07D401/12;C07D403/06;C07D403/12;C07D407/12;C07D413/06;C07D413/12;C07D417/04;C07D417/06 主分类号 C07D257/04
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