<p>A nucleic acid-delivery vehicle for delivering nucleic acids to target cells is provided. The nucleic acid-delivery vehicle comprises a plurality of nanoparticles; and a plurality of nucleic acids. The nanoparticles preferably comprises one or more signal peptides attached to the nanoparticles. The nanoparticles and the nucleic acids are agglomerated to form a nucleic acid-granulation particle having a dimension of at least 20nm. Methods of making the nucleic acid-delivery vehicle and kits comprising nucleic acid-delivery vehicle are also provided.</p>
申请公布号
WO2011139218(A1)
申请公布日期
2011.11.10
申请号
WO2011SE50543
申请日期
2011.05.02
申请人
GENERAL ELECTRIC COMPANY;GE HEALTHCARE BIO-SCIENCES AB;NELSON, JOHN, R.;YOSENICK, TIMOTHY, J.