发明名称 |
METHODS OF DETERMINING SUSCEPTIBILITY OF TUMORS TO TYROSINE KINASE INHIBITORS |
摘要 |
This disclosure provides tyrosine kinase protein and nucleic acid variants, particularly FGFR2 variants, which are linked to drug resistance. The disclosure further provides methods of diagnosis and theranosis, and development of new therapeutic agents using these molecules and fragments thereof, and kits for employing these methods and compositions.
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申请公布号 |
US2011275084(A1) |
申请公布日期 |
2011.11.10 |
申请号 |
US201113047769 |
申请日期 |
2011.03.14 |
申请人 |
THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE |
发明人 |
BYRON SARA ANN;POLLOCK PAMELA MICHELLE |
分类号 |
C12Q1/68;C12Q1/02;C12Q1/48;G01N33/53;G01N33/566;G01N33/573 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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