发明名称 |
STABLE INJECTABLE OIL-IN-WATER DOCETAXEL NANOEMULSION |
摘要 |
The present invention describes Stable injectable oil-in-water Docetaxel nanoemulsion composition having Docetaxel concentrations as high as 20 mg/ml, devoid of hypersensitivity reaction and fluid retention. It employs Synthetic triglycerides, and DSPE PEG-2000, Natural phosphatides, Polyhydric alcohol and Water for injection. In another embodiment lyophilised products with added Cryoprotectants have been described which on reconstitution gives nanoemulsion suitable for parenteral administration. |
申请公布号 |
US2011275705(A1) |
申请公布日期 |
2011.11.10 |
申请号 |
US200913055613 |
申请日期 |
2009.07.22 |
申请人 |
BHARAT SERUMS AND VACCINES LTD. |
发明人 |
DAFTARY GAUTAM VINOD;PAI SRIKANTH ANNAPPA;KULKARNI MANGESH MANIKRAO |
分类号 |
A61K31/337;A61K9/107;A61P35/00 |
主分类号 |
A61K31/337 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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