| 摘要 |
The invention relates generally to optical agents for biomedical applications, including phototherapy. Azide derivatives of some embodiments have an azido group that is directly attached to a phenyl ring having a combination of electron donating groups and electron withdrawing groups. Optical agents of the invention include phototherapeutic agents, including Type 1 phototherapeutic agents that enable a versatile phototherapy platform for treatment of a range of pathological conditions, including the treatment of cancers, stensosis and inflammation. The invention further provides preparations and formulations comprising azide derivatives and related methods of making and using azide optical agents in in vivo or ex vivo biomedical procedures. |
