ULTRA-SENSITIVE DETECTION OF MOLECULES USING DUAL DETECTION METHODS
摘要
Described herein are systems and methods for the detection of and/or determination of a measure of the concentration of analyte molecules or particles in a fluid sample. In some cases, the systems and methods employ techniques to reduce or limit the negative effects associated with non-specific binding events. Certain methods of the present invention involve associating the analyte molecules at least a first type of binding ligand and at least a second type of binding ligand, and spatially segregating the analyte molecules into a plurality of locations on a surface. The presence of an analyte molecule at or in a location may be determined by determining the presence of both the first type of binding ligand and the second type of binding ligand.
申请公布号
WO2011109372(A8)
申请公布日期
2011.11.10
申请号
WO2011US26657
申请日期
2011.03.01
申请人
QUANTERIX CORPORATION;DUFFY, DAVID, C.;RISSIN, DAVID, M.;WALT, DAVID, R.;SONG, LINAN;CHANG, LEI
发明人
DUFFY, DAVID, C.;RISSIN, DAVID, M.;WALT, DAVID, R.;SONG, LINAN;CHANG, LEI