发明名称 |
Porous silicon drug-eluting particles |
摘要 |
<p>The invention provides a biodegradable drug-eluting particle useful for the delivery of diagnostic or therapeutic agents. In certain embodiments, the drug-eluting particle of the invention comprises a biodegradable porous silicon body, a reservoir formed within the porous silicon body having at least one opening to an exterior of the body, wherein the reservoir contains a therapeutic or diagnostic agent, and an agent- permeable seal disposed over the at least one opening. The invention further provides a method for treating a patient to obtain a desired local or systemic physiological or pharmacological effect comprising administering a sustained release drug delivery particle of the invention. The invention also provides methods of fabricating a drug- eluting particle for releasing therapeutic agents.</p> |
申请公布号 |
AU2010246067(A1) |
申请公布日期 |
2011.11.10 |
申请号 |
AU20100246067 |
申请日期 |
2010.05.04 |
申请人 |
PSIVIDA US, INC. |
发明人 |
ASHTON, PAUL;GUO, HONG;CHEN, JIANBING;CANHAM, LEIGH |
分类号 |
A61K9/20;A61K9/22;A61K9/32;A61K47/30 |
主分类号 |
A61K9/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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