发明名称 |
METHODS OF REDUCING SYMPTOMS IN SUBJECTS USING SINGLE DOSAGE FORMS WITH TAPERING RELEASE RATES |
摘要 |
The present invention is directed to methods of reducing symptoms associated with an abrupt reduction in an endogenous or exogenous chemical in subjects, the methods comprising: (a) administering to the subject a single dosage form comprising an active agent, wherein the release rate of the active agent from the single dosage form tapers throughout the administration; and (b) removing the single dosage form from the subjects after the release rate of the active agent is at or below a terminal symptom threshold level.
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申请公布号 |
US2011274740(A1) |
申请公布日期 |
2011.11.10 |
申请号 |
US201113101929 |
申请日期 |
2011.05.05 |
申请人 |
DILIBERTI CHARLES E;MAHASHABDE ANU |
发明人 |
DILIBERTI CHARLES E.;MAHASHABDE ANU |
分类号 |
A61F6/08;A61K31/137;A61K31/465;A61K31/515;A61K31/522;A61K31/551;A61K31/56;A61M31/00;A61M35/00 |
主分类号 |
A61F6/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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