发明名称 |
DERIVATIVES OF BENZOTHIAZINES, PREPARATION THEREOF AND APPLICATION THEREOF AS DRUGS |
摘要 |
The object of the present invention is benzothiazine derivatives having the capability of inhibiting 11&bgr;-HSD1 not only at an enzymatic level but also at a cell level. The compounds of the present invention are of general formula (I). Wherein notably R1 represents a hydrogen or OR1 represents an ester or an ether. R2 represents a naphthyl or a 1,2,3,4-tetrahydro-naphthalene or a biphenyl or phenyl pyridine or a substituted phenyl. R3 represents a methyl or ethyl; R4 and R′4 represent a hydrogen. |
申请公布号 |
KR20110122758(A) |
申请公布日期 |
2011.11.10 |
申请号 |
KR20117022812 |
申请日期 |
2010.03.02 |
申请人 |
PIERRE FABRE MEDICAMENT |
发明人 |
PEREZ MICHEL;LAMOTHE MARIE;JUNQUERO DIDIER;RIVAL YVES |
分类号 |
C07D279/02;A61K31/5415;A61P3/10;C07D275/06 |
主分类号 |
C07D279/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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