发明名称 TREATMENT OF SIRTUIN (SIRT) RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO A SIRTUIN (SIRT)
摘要 <p>The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of a Sirtuin (SIRT), in particular, by targeting natural antisense polynucleotides of a Sirtuin (SIRT). The invention also relates to the identification of these antisense oligonucleotides and their use in treating diseases and disorders associated with the expression of Sirtuins (SIRT)s.</p>
申请公布号 WO2011139387(A1) 申请公布日期 2011.11.10
申请号 WO2011US21052 申请日期 2011.01.13
申请人 OPKO CURNA, LLC;COLLARD, JOSEPH;KHORKOVA SHERMAN, OLGA;COITO, CARLOS;DE LEON, BELINDA 发明人 COLLARD, JOSEPH;KHORKOVA SHERMAN, OLGA;COITO, CARLOS;DE LEON, BELINDA
分类号 C12N15/113;A61K31/7088;A61K48/00;A61P17/00 主分类号 C12N15/113
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