TREATMENT OF SIRTUIN (SIRT) RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO A SIRTUIN (SIRT)
摘要
<p>The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of a Sirtuin (SIRT), in particular, by targeting natural antisense polynucleotides of a Sirtuin (SIRT). The invention also relates to the identification of these antisense oligonucleotides and their use in treating diseases and disorders associated with the expression of Sirtuins (SIRT)s.</p>
申请公布号
WO2011139387(A1)
申请公布日期
2011.11.10
申请号
WO2011US21052
申请日期
2011.01.13
申请人
OPKO CURNA, LLC;COLLARD, JOSEPH;KHORKOVA SHERMAN, OLGA;COITO, CARLOS;DE LEON, BELINDA
发明人
COLLARD, JOSEPH;KHORKOVA SHERMAN, OLGA;COITO, CARLOS;DE LEON, BELINDA