发明名称 |
PHARMACEUTICAL COMPOSITION COMPRISING RACEMIC AMINOPTERIN |
摘要 |
<p>There is disclosed a pharmaceutical composition comprising racemic aminopterin or pharmaceutically acceptable salts thereof. There is further disclosed a method to treat a disorder in a patient comprising administering a therapeutically effective amount of racemic aminopterin or pharmaceutically acceptable salts of racemic aminopterin. More particularly, there is disclosed a method for treating disorders modulated by at least dihydrofolate reductase activity, such as cancers and inflammatory disorders, wherein the method comprises administering to a patient in need thereof a therapeutically effective amount of racemic aminopterin or a pharmaceutically acceptable salt thereof.</p> |
申请公布号 |
EP2384119(A1) |
申请公布日期 |
2011.11.09 |
申请号 |
EP20100733951 |
申请日期 |
2010.01.23 |
申请人 |
SYNTRIX BIOSYSTEMS, INC. |
发明人 |
ZEBALA, JOHN, A.;MAEDA, DEAN, Y.;MORGAN, JOEL, R.;KAHN, STUART, J. |
分类号 |
A61K31/50;A61K31/495;A61K31/519;A61P29/00;A61P35/00 |
主分类号 |
A61K31/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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