METHOD FOR PRODUCING FINE PARTICLE SUSPENSIONS BY MELT EMULSIFICATION

摘要

The invention relates to a method for producing fine particle suspensions by melt emulsification, comprising at least one material having a melting temperature above room temperature, comprising the following steps: (a) transferring at least one pre-emulsion comprising a continuous and a disperse phase in a rotor-stator machine, a rotor-rotor machine, or to a continuous and/or disperse phase; (b) optionally adding one or more further components to the at least one pre-emulsion in the rotor-stator machine; (c) emulsifying the at least one pre-emulsion by means of mechanical shearing and/or stretching and/or turbulence at a temperature no greater than 10 K above the melting temperature of the at least one material having a melting temperature above room temperature, or at a temperature no less than 10 K below and no greater than 10 K above the glass transition temperature or the melting temperature, as long as the material having a melting temperature above room temperature is a polymer, for producing a fine particle emulsion; and (d) cooling the fine particle emulsion for producing a fine particle suspension; wherein the disperse phase portion is in the range of 85% to 99.5% at least in step (c).