发明名称 |
RAD51C as a human cancer susceptibility gene |
摘要 |
<p>The invention discloses an in vitro method for determining a predisposition of a subject for developing a cancer on the basis of analyzing a sample of the subject for an alteration of at least one allele of the RAD51C gene. Further disclosed are in vitro methods for assessing a pathological progression of a cancer and for assessing at least one RAD51C gene alteration in a cell, a kit for determining a predisposition of a subject for developing a cancer, and certain uses of oligonucleotides for determining the presence of at least one mono-allelic germ-line mutation of the RAD51C gene.</p> |
申请公布号 |
EP2385135(A1) |
申请公布日期 |
2011.11.09 |
申请号 |
EP20100159524 |
申请日期 |
2010.04.09 |
申请人 |
HANENBERG, HELMUT |
发明人 |
HANENBERG, HELMUT;SCHMUTZLER, RITA;MEINDL, ALFONS;WIEK, CONSTANZE;ERVEN, VERENA;FREUND, MARCEL |
分类号 |
C12Q1/68 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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