| 发明名称 |
MODULATION OF PD-1 INTERACTIONS WITH ITS LIGANDS |
| 摘要 |
<p>Disclosed are methods for downmodulating an immune response comprising contacting an immune cell with an agent that modulates the interaction between PD-1 and a PD-1 (e.g., soluble forms of PD-1 or PD-1 ligand or antibodies to PD-1) to thereby modulate the immune response.</p> |
| 申请公布号 |
CA2442182(C) |
申请公布日期 |
2011.11.08 |
| 申请号 |
CA20022442182 |
申请日期 |
2002.04.02 |
| 申请人 |
WYETH |
发明人 |
CARRENO, BEATRIZ M.;LEONARD, JOHN |
| 分类号 |
A61K38/12;C12N15/09;A61K38/00;A61K38/17;A61K39/395;A61K45/00;A61K45/06;A61P25/28;A61P37/06;A61P43/00;C07K14/705;C07K16/28;C12N5/06 |
主分类号 |
A61K38/12 |
| 代理机构 |
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代理人 |
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| 主权项 |
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